Julio Rodriguez, 31, of Hartford, was killed around 1 a.m. in the area of Exit 85 in Hartford, said the Connecticut State Police.
Troopers said the two motorcycles were traveling on Route 15 north when both drivers lost control of their bikes at the same time and struck the right shoulder metal guardrails.
The driver of the other motorcycle, Charles Wooding, 24, of Vernon, suffered non-life threatening injuries and was transported to Hartford Hospital.
Route 15 was closed for more than five hours as state police investigated the crash.
Click here to follow Daily Voice Fairfield and receive free news updates.